Major drug resistance mutations to HIV-1 protease inhibitors (PI) among patients exposed to PI class failing antiretroviral therapy in São Paulo State, Brazil.

Major drug resistance mutations to HIV-1 protease inhibitors (PI) among patients exposed to PI class failing antiretroviral therapy in São Paulo State, Brazil.

BACKGROUND:Protease inhibitors (PI) are especially important in salvage therapy. Previous treatment failure with a PI containing regimen may elicit resistance mutations, reducing PI susceptibility and limiting treatment options. The aim of this study was to describe major PI mutations among patients...

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Bibliographic Details
Main Authors: Giselle de Faria Romero Soldi, Isadora Coutinho Ribeiro, Cintia Mayumi Ahagon, Luana Portes Ozório Coelho, Gabriela Bastos Cabral, Giselle Ibette Silva López Lopes, João Leandro de Paula Ferreira, Luís Fernando de Macedo Brígido, Salvage Therapy Working Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0223210

Internet

https://doi.org/10.1371/journal.pone.0223210

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