Decreased expression of CCL17 in the disrupted nasal polyp epithelium and its regulation by IL-4 and IL-5.

Decreased expression of CCL17 in the disrupted nasal polyp epithelium and its regulation by IL-4 and IL-5.

BACKGROUND:In airway epithelium, thymus and activation-regulated chemokine (CCL17) and macrophage-derived chemokine (CCL22) are induced by defective epithelial barriers such as E-cadherin and attract the effector cells of Th2 immunity. However, the association between the epithelial barrier and CCL1...

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Main Authors: Byoungjae Kim, Hyun-Ji Lee, Nu-Ri Im, Doh Young Lee, Ha Kyun Kim, Cha Young Kang, Il-Ho Park, Seung Hoon Lee, Heung-Man Lee, Sang Hag Lee, Seung-Kuk Baek, Tae Hoon Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5945007?pdf=render

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http://europepmc.org/articles/PMC5945007?pdf=render

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