Non-SMC Element 2 (NSMCE2) of the SMC5/6 Complex Helps to Resolve Topological Stress

Non-SMC Element 2 (NSMCE2) of the SMC5/6 Complex Helps to Resolve Topological Stress

The structural maintenance of chromosomes (SMC) protein complexes shape and regulate the structure and dynamics of chromatin, thereby controlling many chromosome-based processes such as cell cycle progression, differentiation, gene transcription and DNA repair. The SMC5/6 complex is previously descr...

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Bibliographic Details
Main Authors: Dideke E. Verver, Yi Zheng, Dave Speijer, Ron Hoebe, Henk L. Dekker, Sjoerd Repping, Jan Stap, Geert Hamer
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:International Journal of Molecular Sciences
Subjects:
Structural Maintenance of Chromosomes 5/6 complex (SMC5/6)
Non-SMC Element 2 (NSMCE2)
Topoisomerase II α (TOP2A)
DNA double-strand breaks (DSBs)
Ionizing Radiation (IR)
CRISPR-Cas9
Online Access:http://www.mdpi.com/1422-0067/17/11/1782

Internet

http://www.mdpi.com/1422-0067/17/11/1782

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