Effect of DNA Glycosylases OGG1 and Neil1 on Oxidized G-Rich Motif in the <i>KRAS</i> Promoter
The promoter of the <i>Kirsten ras</i> (<i>KRAS</i>) proto-oncogene contains, upstream of the transcription start site, a quadruplex-forming motif called 32R with regulatory functions. As guanine under oxidative stress can be oxidized to 8-oxoguanine (8OG), we investigated th...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-01-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/22/3/1137 |