TSPO Ligands Promote Cholesterol Efflux and Suppress Oxidative Stress and Inflammation in Choroidal Endothelial Cells

TSPO Ligands Promote Cholesterol Efflux and Suppress Oxidative Stress and Inflammation in Choroidal Endothelial Cells

Choroidal endothelial cells supply oxygen and nutrients to retinal pigment epithelial (RPE) cells and photoreceptors, recycle metabolites, and dispose of metabolic waste through the choroidal blood circulation. Death of the endothelial cells of the choroid may cause abnormal deposits including unest...

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Bibliographic Details
Main Authors: Lincoln Biswas, Fahad Farhan, James Reilly, Chris Bartholomew, Xinhua Shu
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:International Journal of Molecular Sciences
Subjects:
TSPO
cholesterol efflux
oxidative stress
inflammation
choroidal endothelial cells
age-related macular degeneration
Online Access:https://www.mdpi.com/1422-0067/19/12/3740

Internet

https://www.mdpi.com/1422-0067/19/12/3740

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