Exploring the Mitochondrial Degradome by the TAILS Proteomics Approach in a Cellular Model of Parkinson’s Disease

Exploring the Mitochondrial Degradome by the TAILS Proteomics Approach in a Cellular Model of Parkinson’s Disease

Parkinson’s disease (PD) is the second most frequent neurodegenerative disease worldwide and the availability of early biomarkers and novel biotargets represents an urgent medical need. The main pathogenetic hallmark of PD is the specific loss of nigral dopaminergic neurons, in which mitochondrial d...

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Bibliographic Details
Main Authors: Marta Lualdi, Maurizio Ronci, Mara Zilocchi, Federica Corno, Emily S. Turilli, Mauro Sponchiado, Antonio Aceto, Tiziana Alberio, Mauro Fasano
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
proteomics
degradomics
TAILS N-terminomics
mitochondria
Parkinson’s disease
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00195/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2019.00195/full

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