Use of Single-Chain Antibody Derivatives for Targeted Drug Delivery

Abstract Single-chain antibodies (scFvs), which contain only the variable domains of full-length antibodies, are relatively small molecules that can be used for selective drug delivery. In this review, we discuss how scFvs help improve the specificity and efficiency of drugs. Small interfering RNA (...

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Bibliographic Details
Main Authors: Yaghoub Safdari, Vahideh Ahmadzadeh, Masoumeh Khalili, Hossein Zarei Jaliani, Vahid Zarei, Vahid Erfani-Moghadam
Format: Article
Language:English
Published: BMC 2016-04-01
Series:Molecular Medicine
Online Access:http://link.springer.com/article/10.2119/molmed.2016.00043