Oral uricase eliminates blood uric acid in the hyperuricemic pig model.

An elevated level of serum uric acid-hyperuricemia, is strongly associated with the development of gout and chronic kidney disease (CKD) which is often accompanied by a significantly reduced glomerular filtration rate (GFR). In the present study, we investigated the extra-renal elimination of uric a...

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Main Authors: Paulina Szczurek, Nadia Mosiichuk, Jarosław Woliński, Tetiana Yatsenko, Danica Grujic, Liudmyla Lozinska, Marek Pieszka, Ewa Święch, Stefan Grzegorz Pierzynowski, Kateryna Goncharova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5464639?pdf=render