Bayesian nonparametric discovery of isoforms and individual specific quantification

Bayesian nonparametric discovery of isoforms and individual specific quantification

Alternative splicing leads to transcript isoform diversity. Here, Aguiar et al. develop biisq, a Bayesian nonparametric approach to discover and quantify isoforms from RNA-seq data.

Bibliographic Details
Main Authors: Derek Aguiar, Li-Fang Cheng, Bianca Dumitrascu, Fantine Mordelet, Athma A. Pai, Barbara E. Engelhardt
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03402-w
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spelling doaj-6a28ab9e7cc640d796b018e6bdb3af532021-05-11T10:17:00ZengNature Publishing GroupNature Communications2041-17232018-04-019111210.1038/s41467-018-03402-wBayesian nonparametric discovery of isoforms and individual specific quantificationDerek Aguiar0Li-Fang Cheng1Bianca Dumitrascu2Fantine Mordelet3Athma A. Pai4Barbara E. Engelhardt5Department of Computer Science, Princeton UniversityDepartment of Electrical Engineering, Princeton UniversityLewis-Sigler Institute, Princeton UniversityInstitute for Genome Sciences and Policy, Duke UniversityDepartment of Biology, Massachusetts Institute of TechnologyDepartment of Computer Science, Princeton UniversityAlternative splicing leads to transcript isoform diversity. Here, Aguiar et al. develop biisq, a Bayesian nonparametric approach to discover and quantify isoforms from RNA-seq data.https://doi.org/10.1038/s41467-018-03402-w
collection DOAJ
language English
format Article
sources DOAJ
author Derek Aguiar
Li-Fang Cheng
Bianca Dumitrascu
Fantine Mordelet
Athma A. Pai
Barbara E. Engelhardt
spellingShingle Derek Aguiar
Li-Fang Cheng
Bianca Dumitrascu
Fantine Mordelet
Athma A. Pai
Barbara E. Engelhardt
Bayesian nonparametric discovery of isoforms and individual specific quantification
Nature Communications
author_facet Derek Aguiar
Li-Fang Cheng
Bianca Dumitrascu
Fantine Mordelet
Athma A. Pai
Barbara E. Engelhardt
author_sort Derek Aguiar
title Bayesian nonparametric discovery of isoforms and individual specific quantification
title_short Bayesian nonparametric discovery of isoforms and individual specific quantification
title_full Bayesian nonparametric discovery of isoforms and individual specific quantification
title_fullStr Bayesian nonparametric discovery of isoforms and individual specific quantification
title_full_unstemmed Bayesian nonparametric discovery of isoforms and individual specific quantification
title_sort bayesian nonparametric discovery of isoforms and individual specific quantification
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2018-04-01
description Alternative splicing leads to transcript isoform diversity. Here, Aguiar et al. develop biisq, a Bayesian nonparametric approach to discover and quantify isoforms from RNA-seq data.
url https://doi.org/10.1038/s41467-018-03402-w
work_keys_str_mv AT derekaguiar bayesiannonparametricdiscoveryofisoformsandindividualspecificquantification
AT lifangcheng bayesiannonparametricdiscoveryofisoformsandindividualspecificquantification
AT biancadumitrascu bayesiannonparametricdiscoveryofisoformsandindividualspecificquantification
AT fantinemordelet bayesiannonparametricdiscoveryofisoformsandindividualspecificquantification
AT athmaapai bayesiannonparametricdiscoveryofisoformsandindividualspecificquantification
AT barbaraeengelhardt bayesiannonparametricdiscoveryofisoformsandindividualspecificquantification
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