Bayesian nonparametric discovery of isoforms and individual specific quantification

Alternative splicing leads to transcript isoform diversity. Here, Aguiar et al. develop biisq, a Bayesian nonparametric approach to discover and quantify isoforms from RNA-seq data.

Bibliographic Details
Main Authors: Derek Aguiar, Li-Fang Cheng, Bianca Dumitrascu, Fantine Mordelet, Athma A. Pai, Barbara E. Engelhardt
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03402-w