Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension

<p>Abstract</p> <p>Background</p> <p>Endothelin-1 signalling plays an important role in pathogenesis of pulmonary hypertension. Although different endothelin-A receptor antagonists are developed, a novel therapeutic option to cure the disease is still needed. This study...

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Bibliographic Details
Main Authors: Brandes Ralf P, Janssen Wiebke, Cornitescu Teodora, Sydykov Akylbek, Dahal Bhola K, Luitel Himal, Kojonazarov Baktybek, Kosanovic Djuro, Davie Neil, Ghofrani Hossein A, Weissmann Norbert, Grimminger Friedrich, Seeger Werner, Schermuly Ralph T
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/12/1/87