11C‐PK11195 PET–based molecular study of microglia activation in SOD1 amyotrophic lateral sclerosis

11C‐PK11195 PET–based molecular study of microglia activation in SOD1 amyotrophic lateral sclerosis

Abstract Objective Neuroinflammation is considered a key driver for neurodegeneration in several neurological diseases, including amyotrophic lateral sclerosis (ALS). SOD1 mutations cause about 20% of familial ALS, and related pathology might generate microglial activation triggering neurodegenerati...

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Bibliographic Details
Main Authors: Giacomo Tondo, Leonardo Iaccarino, Chiara Cerami, Giovanna Emilia Vanoli, Luca Presotto, Valeria Masiello, Angela Coliva, Fabrizio Salvi, Ilaria Bartolomei, Lorena Mosca, Christian Lunetta, Daniela Perani
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.51112

Internet

https://doi.org/10.1002/acn3.51112

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