Comparison of metamizole and paracetamol effects on colonic anastomosis and fibroblast activities in Wistar rats

Abstract Background Leakage following colorectal anastomosis surgery causes various complications associated with high morbidity and mortality, especially in pediatric patients. It might be caused by the use of non-steroidal anti-inflammatory drugs (NSAIDs) as postoperative analgesics. This study ai...

Full description

Bibliographic Details
Main Authors: Eko Purnomo, Dwi Aris Agung Nugrahaningsih, Nunik Agustriani, Gunadi
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Pharmacology and Toxicology
Subjects:
Online Access:https://doi.org/10.1186/s40360-020-0383-x