The hepatic lipidome and HNF4α and SHBG expression in human liver

Low plasma levels of sex hormone-binding globulin (SHBG) are a marker for obesity, insulin resistance, non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes. The transcription factor HNF4α is a major determinant of hepatic SHBG expression and thereby serum SHBG levels, and mediates in part t...

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Bibliographic Details
Main Authors: Stephen J Winters, Charles R Scoggins, Duke Appiah, Dushan T Ghooray
Format: Article
Language:English
Published: Bioscientifica 2020-10-01
Series:Endocrine Connections
Subjects:
Online Access:https://ec.bioscientifica.com/view/journals/ec/9/10/EC-20-0401.xml