The hepatic lipidome and HNF4α and SHBG expression in human liver
Low plasma levels of sex hormone-binding globulin (SHBG) are a marker for obesity, insulin resistance, non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes. The transcription factor HNF4α is a major determinant of hepatic SHBG expression and thereby serum SHBG levels, and mediates in part t...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Bioscientifica
2020-10-01
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Series: | Endocrine Connections |
Subjects: | |
Online Access: | https://ec.bioscientifica.com/view/journals/ec/9/10/EC-20-0401.xml |