Hippocampal desynchronization of functional connectivity prior to the onset of status epilepticus in pilocarpine-treated rats.

Status epilepticus (SE), a pro-epileptogenic brain insult in rodent models of temporal lobe epilepsy, is successfully induced by pilocarpine in some, but not all, rats. This study aimed to identify characteristic alterations within the hippocampal neural network prior to the onset of SE. Sixteen mic...

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Bibliographic Details
Main Authors: Chi-Han Wang, Chou P Hung, Ming-Teh Chen, Yang-Hsin Shih, Yung-Yang Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3387264?pdf=render