Aberrant Development and Synaptic Transmission of Cerebellar Cortex in a VPA Induced Mouse Autism Model

Aberrant Development and Synaptic Transmission of Cerebellar Cortex in a VPA Induced Mouse Autism Model

Autistic spectral disorder (ASD) is a prevalent neurodevelopmental disease that affects multiple brain regions. Both clinical and animal studies have revealed the possible involvement of the cerebellum in ASD pathology. In this study, we generated a rodent ASD model through a single prenatal adminis...

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Bibliographic Details
Main Authors: Ruanna Wang, Jiahui Tan, Junxiu Guo, Yuhan Zheng, Qing Han, Kwok-Fai So, Jiandong Yu, Li Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
autism
cerebellum
environmental exposure
motor learning
postnatal development
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00500/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00500/full

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