Cinnamaldehyde and cinnamaldehyde derivatives reduce virulence in <it>Vibrio </it>spp. by decreasing the DNA-binding activity of the quorum sensing response regulator LuxR

<p>Abstract</p> <p>Background</p> <p>To date, only few compounds targeting the AI-2 based quorum sensing (QS) system are known. In the present study, we screened cinnamaldehyde and substituted cinnamaldehydes for their ability to interfere with AI-2 based QS. The mechan...

Full description

Bibliographic Details
Main Authors: Van Calenbergh Serge, Bossier Peter, Miyamoto Carol, Defoirdt Tom, Brackman Gilles, Nelis Hans, Coenye Tom
Format: Article
Language:English
Published: BMC 2008-09-01
Series:BMC Microbiology
Online Access:http://www.biomedcentral.com/1471-2180/8/149