Immunoprofiling of human uterine mast cells identifies three phenotypes and expression of ERβ and glucocorticoid receptor [version 2; referees: 2 approved]

Background: Human mast cells (MCs) are long-lived tissue-resident immune cells characterised by granules containing the proteases chymase and/or tryptase. Their phenotype is modulated by their tissue microenvironment. The human uterus has an outer muscular layer (the myometrium) surrounding the endo...

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Bibliographic Details
Main Authors: Bianca De Leo, Arantza Esnal-Zufiaurre, Frances Collins, Hilary O.D. Critchley, Philippa T.K. Saunders
Format: Article
Language:English
Published: F1000 Research Ltd 2017-06-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/6-667/v2