Dicer1 ablation in the mouse epididymis causes dedifferentiation of the epithelium and imbalance in sex steroid signaling.

BACKGROUND: The postnatal development of the epididymis is a complex process that results in a highly differentiated epithelium, divided into several segments. Recent studies indicate a role for RNA interference (RNAi) in the development of the epididymis, however, the actual requirement for RNAi ha...

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Bibliographic Details
Main Authors: Ida Björkgren, Lauri Saastamoinen, Anton Krutskikh, Ilpo Huhtaniemi, Matti Poutanen, Petra Sipilä
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3368854?pdf=render