The Diversity of Encephalitogenic CD4+ T Cells in Multiple Sclerosis and Its Animal Models
Autoreactive CD4+ T cells, which target antigens in central nervous system (CNS) myelin, are widely believed to play a critical role in the pathogenesis of multiple sclerosis (MS) in concert with other immune effectors. This theory is supported by data from animal model experiments, genome-wide asso...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-01-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | http://www.mdpi.com/2077-0383/8/1/120 |