Proinflammatory Cytokine Modulates Intracellular Calcium Handling and Enhances Ventricular Arrhythmia Susceptibility

Proinflammatory Cytokine Modulates Intracellular Calcium Handling and Enhances Ventricular Arrhythmia Susceptibility

Background: The mechanism of Interleukin-17 (IL-17) induced ventricular arrhythmia (VA) remains unclear. This study aimed to investigate the effect of intracellular calcium (Cai) handling and VA susceptibility by IL-17.Methods: The electrophysiological properties of isolated perfused rabbit hearts u...

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Bibliographic Details
Main Authors: Yung-Nan Tsai, Ya-Wen Hsiao, Shien-Fong Lin, Yi-Hsin Chan, Yu-Cheng Hsieh, Wei-Hua Tang, An-Sheng Lee, Yu-Ting Huang, Hsing-Yuan Li, Tze-Fan Chao, Satoshi Higa, Tsu-Juey Wu, Shih-Lin Chang, Shih-Ann Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
alternans
the maximum calcium transient
IL-17 neutralizer
IL-17
ventricular arrhythmias
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.623510/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2021.623510/full

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