Theta-phase closed-loop stimulation induces motor paradoxical responses in the rat model of Parkinson disease

Background: High-frequency deep brain stimulation (DBS) has become a widespread therapy used in the treatment of Parkinson's Disease (PD) and other diseases. Although it has proved beneficial, much recent attention has been centered around the potential of new closed-loop DBS implementations. O...

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Bibliographic Details
Main Authors: Ivan Cordon, María Jesús Nicolás, Sandra Arrieta, Manuel Alegre, Julio Artieda, Miguel Valencia
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Brain Stimulation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1935861X1730935X