Double domain polyethylenimine-based nanoparticles for integrin receptor mediated delivery of plasmid DNA

Abstract The objective of the present study is to conjugate L-thyroxine PEI derivative onto another PEI to compensate the amine content of the whole structure which has been utilized for the ligand conjugation. Since αvβ3 integrin receptors are over-expressed on cancer cells and there is binding sit...

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Bibliographic Details
Main Authors: Hossein Sadeghpour, Bahman Khalvati, Elaheh Entezar-Almahdi, Narjes Savadi, Samira Hossaini Alhashemi, Mohammad Raoufi, Ali Dehshahri
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25277-z