Development of a Cell-Based Functional Assay for the Detection of Clostridium botulinum Neurotoxin Types A and E

The standard procedure for definitive detection of BoNT-producing Clostridia is a culture method combined with neurotoxin detection using a standard mouse bioassay (MBA). The mouse bioassay is highly sensitive and specific, but it is expensive and time-consuming, and there are ethical concerns due t...

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Bibliographic Details
Main Authors: Uma Basavanna, Tim Muruvanda, Eric W. Brown, Shashi K. Sharma
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:International Journal of Microbiology
Online Access:http://dx.doi.org/10.1155/2013/593219