The "alternative" choice of constitutive exons throughout evolution.

Alternative cassette exons are known to originate from two processes-exonization of intronic sequences and exon shuffling. Herein, we suggest an additional mechanism by which constitutively spliced exons become alternative cassette exons during evolution. We compiled a dataset of orthologous exons f...

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Bibliographic Details
Main Authors: Galit Lev-Maor, Amir Goren, Noa Sela, Eddo Kim, Hadas Keren, Adi Doron-Faigenboim, Shelly Leibman-Barak, Tal Pupko, Gil Ast
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2077895?pdf=render