Analysis of false-negative rapid diagnostic tests for symptomatic malaria in the Democratic Republic of the Congo

Analysis of false-negative rapid diagnostic tests for symptomatic malaria in the Democratic Republic of the Congo

Abstract The majority of Plasmodium falciparum malaria diagnoses in Africa are made using rapid diagnostic tests (RDTs) that detect histidine-rich protein 2. Increasing reports of false-negative RDT results due to parasites with deletions of the pfhrp2 and/or pfhrp3 genes (pfhrp2/3) raise concern ab...

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Bibliographic Details
Main Authors: Jonathan B. Parr, Eddy Kieto, Fernandine Phanzu, Paul Mansiangi, Kashamuka Mwandagalirwa, Nono Mvuama, Ange Landela, Joseph Atibu, Solange Umesumbu Efundu, Jean W. Olenga, Kyaw Lay Thwai, Camille E. Morgan, Madeline Denton, Alison Poffley, Jonathan J. Juliano, Pomie Mungala, Joris L. Likwela, Eric M. Sompwe, Eric Rogier, Antoinette K. Tshefu, Adrien N’Siala, Albert Kalonji
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85913-z

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https://doi.org/10.1038/s41598-021-85913-z

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