Grindelia squarrosa Extract and Grindelic Acid Modulate Pro-inflammatory Functions of Respiratory Epithelium and Human Macrophages

Grindelia squarrosa Extract and Grindelic Acid Modulate Pro-inflammatory Functions of Respiratory Epithelium and Human Macrophages

Aim of the study: Both nasal and bronchial epithelial cells have evolved sophisticated mechanisms involved in cellular response to bacterial infection. Recognition of pathogens by TLR receptors activate the NF-κB transcription factor, and lead to production of wide spectrum of cytokines (TNF-α, IL-1...

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Bibliographic Details
Main Authors: Barbara Gierlikowska, Agnieszka Filipek, Wojciech Gierlikowski, Dominika Kania, Joanna Stefańska, Urszula Demkow, Anna K. Kiss
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
Grindelia squarrosa
grindelic acid
inflammation
cold syndrome
respiratory epithelium
macrophages
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.534111/full

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https://www.frontiersin.org/articles/10.3389/fphar.2020.534111/full

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