Rg3-enriched Korean Red Ginseng extract inhibits blood-brain barrier disruption in an animal model of multiple sclerosis by modulating expression of NADPH oxidase 2 and 4

Background: Multiple sclerosis (MS) and its animal model, the experimental autoimmune encephalomyelitis (EAE), are primarily characterized as dysfunction of the blood-brain barrier (BBB). Ginsenoside-Rg3-enriched Korean Red Ginseng extract (Rg3-KRGE) is known to exert neuroprotective, anti-inflammat...

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Bibliographic Details
Main Authors: Min Jung Lee, Jong Hee Choi, Jinhee Oh, Young Hyun Lee, Jun-Gyo In, Byung-Joon Chang, Seung-Yeol Nah, Ik-Hyun Cho
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Journal of Ginseng Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1226845320301366