Platelet-Derived Biomaterials Inhibit Nicotine-Induced Intervertebral Disc Degeneration Through Regulating IGF-1/AKT/IRS-1 Signaling Axis

Apart from aging process, adult intervertebral disc (IVD) undergoes various degenerative processes. However, the nicotine has not been well identified as a contributing etiology. According to a few studies, nicotine ingestion through smoking, air or clothing may significantly accumulate in active as...

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Bibliographic Details
Main Authors: Wen-Cheng Lo, Chi-Sheng Chiou, Feng-Chou Tsai, Chun-Hao Chan, Samantha Mao, Yue-Hua Deng, Chia-Yu Wu, Bou-Yue Peng, Win-Ping Deng
Format: Article
Language:English
Published: SAGE Publishing 2021-09-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/09636897211045319