Identification of Intracellular β-Barrel Residues Involved in Ion Selectivity in the Mechanosensitive Channel of Thermoanaerobacter tengcongensis

Identification of Intracellular β-Barrel Residues Involved in Ion Selectivity in the Mechanosensitive Channel of Thermoanaerobacter tengcongensis

The mechanosensitive channel of small conductance (MscS) is a bacterial membrane pore that senses membrane tension and protects cells from lysis by releasing osmolytes. MscS is a homoheptameric channel with a cytoplasmic domain with seven portals and a β-barrel opening to the cytoplasm. TtMscS, an M...

Full description

Bibliographic Details
Main Authors: Yingcai Song, Bing Zhang, Fei Guo, Maojun Yang, Yang Li, Zhi-Qiang Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Physiology
Subjects:
TtMscS
anion selectivity
β-barrel
selective filter
patch-clamp
single mutation
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00832/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2017.00832/full

Similar Items