Mechanisms underlying the tissue-specific and regulated activity of the Gnrhr promoter in mammals.

Mechanisms underlying the tissue-specific and regulated activity of the Gnrhr promoter in mammals.

The GnRH receptor (GnRHR) plays a central role in the development and maintenance of reproductive function in mammals. Following stimulation by GnRH originating from the hypothalamus, GnRHR triggers multiple signalling events that ultimately stimulate the synthesis and the periodic release of the go...

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Bibliographic Details
Main Authors: Anne-Laure eSchang, Bruno eQuérat, Violaine eSimon, Ghislaine eGarrel, Christian eBleux, Raymond eCounis, Joëlle eCohen-Tannoudji, Jean-Noël eLaverrière
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-12-01
Series:Frontiers in Endocrinology
Subjects:
Homeodomain Proteins
Promoter Regions, Genetic
Steroidogenic Factor 1
Transcription, Genetic
Transgenic mice
GnRH receptor
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00162/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00162/full

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