Proteins that promote filopodia stability, but not number, lead to more axonal-dendritic contacts.

Dendritic filopodia are dynamic protrusions that are thought to play an active role in synaptogenesis and serve as precursors to spine synapses. However, this hypothesis is largely based on a temporal correlation between filopodia formation and synaptogenesis. We investigated the role of filopodia i...

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Bibliographic Details
Main Authors: Pamela Arstikaitis, Catherine Gauthier-Campbell, Kun Huang, Alaa El-Husseini, Timothy H Murphy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3049770?pdf=render