Visualizing presynaptic calcium dynamics and vesicle fusion with a single genetically encoded reporter at individual synapses

Synaptic transmission depends on the influx of calcium into the presynaptic compartment, which drives neurotransmitter release. Genetically encoded reporters are widely used tools to understand these processes, particularly pHluorin-based reporters that report vesicle exocytosis and endocytosis thro...

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Bibliographic Details
Main Authors: Rachel E Jackson, Juan Burrone
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-07-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsyn.2016.00021/full