Indoleamine 2,3 dioxygenase (IDO) level as a marker for significant coronary artery disease

Abstract Background Indoleamine 2,3 dioxygenase (IDO), the rate-limiting enzyme in the kynurenine (Kyn) pathway of tryptophan (Trp) degradation, is modulated by inflammation, and is regarded as a key molecule driving immunotolerance and immunosuppressive mechanisms. Little is known about IDO activit...

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Bibliographic Details
Main Authors: Nattawut Wongpraparut, Ploy Pengchata, Sudarat Piyophirapong, Pariya Panchavinnin, Rungtiwa Pongakasira, Noppadol Arechep, Kanda Kasetsinsombat, Kittipong Maneechotesuwan
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Cardiovascular Disorders
Subjects:
IDO
Online Access:https://doi.org/10.1186/s12872-021-02140-0