Nitric oxide facilitates delivery and mediates improved outcome of autologous bone marrow mononuclear cells in a rodent stroke model.

Nitric oxide facilitates delivery and mediates improved outcome of autologous bone marrow mononuclear cells in a rodent stroke model.

Bone marrow mononuclear cells (MNC) represent an investigational treatment for stroke. The objective of this study was to determine the relevance of vasoactive mediators, generated in response to MNC injection, as factors regulating cerebral perfusion (CP), the biodistribution of MNC, and outcome in...

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Bibliographic Details
Main Authors: Mallikarjunarao Kasam, Bing Yang, Roger Strong, Krystal Schaar, Vivek Misra, Xiaopei Xi, James C Grotta, Jaroslaw Aronowski, Sean I Savitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3296739?pdf=render

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http://europepmc.org/articles/PMC3296739?pdf=render

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