Endogenous Pancreatic Enzyme Activity Levels Show no Significant Effect on Human Islet Isolation Yield

Despite advances in human islet isolation, islet yield remains inconsistent and unreliable. In recent studies, it has been suggested that serine proteases, in particular trypsin, have been shown to have a damaging effect on islet yield. This study evaluated enzyme activity levels throughout 42 human...

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Bibliographic Details
Main Authors: Natisha L. Rose, Monica M. Palcic, A. M. James Shapiro, Jonathan R. T. Lakey Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2004-03-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000004773301834