Increased expression of fragmented tRNA promoted neuronal necrosis
Abstract Neuronal necrosis induced by excessive glutamate release is well known to contribute morbidity and mortality in ischemic stroke. Over the past decades, strategies on targeting glutamate receptor did not achieve desirable clinical outcomes. Finding the downstream mechanism of the glutamate r...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-08-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-021-04108-6 |