Down-regulation of tenascin-C inhibits breast cancer cells development by cell growth, migration, and adhesion impairment.
Tenascin-C (TNC) is an extracellular matrix (ECM) glycoprotein that plays an important role in cell proliferation, migration, and tumour invasion in various cancers. TNC is one of the main protein overexpressed in breast cancer, indicating a role for this ECM molecule in cancer pathology. In this st...
Main Authors: | Dariusz Wawrzyniak, Małgorzata Grabowska, Paweł Głodowicz, Konrad Kuczyński, Bogna Kuczyńska, Agnieszka Fedoruk-Wyszomirska, Katarzyna Rolle |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0237889 |
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