Down-regulation of tenascin-C inhibits breast cancer cells development by cell growth, migration, and adhesion impairment.

Tenascin-C (TNC) is an extracellular matrix (ECM) glycoprotein that plays an important role in cell proliferation, migration, and tumour invasion in various cancers. TNC is one of the main protein overexpressed in breast cancer, indicating a role for this ECM molecule in cancer pathology. In this st...

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Bibliographic Details
Main Authors: Dariusz Wawrzyniak, Małgorzata Grabowska, Paweł Głodowicz, Konrad Kuczyński, Bogna Kuczyńska, Agnieszka Fedoruk-Wyszomirska, Katarzyna Rolle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0237889