An Improved Dehydroepiandrosterone-Induced Rat Model of Polycystic Ovary Syndrome (PCOS): Post-pubertal Improve PCOS's Features

An Improved Dehydroepiandrosterone-Induced Rat Model of Polycystic Ovary Syndrome (PCOS): Post-pubertal Improve PCOS's Features

Complete animal models investigating the pathogenesis and treatment of polycystic ovarian syndrome (PCOS) are not completely established. Although dehydroepiandrosterone (DHEA)-induced pre-pubertal rat model for PCOS has been widely used, the model exhibits weaknesses such as decreased ovary weight....

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Bibliographic Details
Main Authors: Eun-Jeong Kim, Minhee Jang, Jong Hee Choi, Kyoung Sun Park, Ik-Hyun Cho
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Endocrinology
Subjects:
polycystic ovary syndrome model
dehydroepiandrosterone
post-puberty
rats
improved model
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00735/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2018.00735/full

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