Generation of Knockout and Transgenic Zebrafish to Characterize Abcc4 Functions in Detoxification and Efflux of Lead

Generation of Knockout and Transgenic Zebrafish to Characterize Abcc4 Functions in Detoxification and Efflux of Lead

Lead (Pb) is one of the major heavy metals that are toxic to vertebrates and usually considered as environmental pollutants. ABCC4/MRP4 is an organic anion transporter that mediates cellular efflux of a wide range of exogenous and endogenous compounds such as cyclic nucleotides and anti-cancer drugs...

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Bibliographic Details
Main Authors: Xing Lu, Yong Long, Xixi Li, Lang Zhang, Qing Li, Hua Wen, Shan Zhong, Zongbin Cui
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
zebrafish
Abcc4
lead
detoxification
efflux transporter
transgenesis
Online Access:https://www.mdpi.com/1422-0067/22/4/2054

Internet

https://www.mdpi.com/1422-0067/22/4/2054

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