Differentiation of human embryonic stem cells into cells with corneal keratocyte phenotype.

Differentiation of human embryonic stem cells into cells with corneal keratocyte phenotype.

Corneal transparency depends on a unique extracellular matrix secreted by stromal keratocytes, mesenchymal cells of neural crest lineage. Derivation of keratocytes from human embryonic stem (hES) cells could elucidate the keratocyte developmental pathway and open a potential for cell-based therapy f...

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Bibliographic Details
Main Authors: Audrey A Chan, Andrew J Hertsenberg, Martha L Funderburgh, Mary M Mann, Yiqin Du, Katherine A Davoli, Jocelyn Danielle Mich-Basso, Lei Yang, James L Funderburgh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3578879?pdf=render

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http://europepmc.org/articles/PMC3578879?pdf=render

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