Identification of 67 Pleiotropic Genes Associated With Seven Autoimmune/Autoinflammatory Diseases Using Multivariate Statistical Analysis

Identification of 67 Pleiotropic Genes Associated With Seven Autoimmune/Autoinflammatory Diseases Using Multivariate Statistical Analysis

Although genome-wide association studies (GWAS) have a dramatic impact on susceptibility locus discovery, this univariate approach has limitations in detecting complex genotype-phenotype correlations. Multivariate analysis is essential to identify shared genetic risk factors acting through common bi...

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Bibliographic Details
Main Authors: Xiaocan Jia, Nian Shi, Yu Feng, Yifan Li, Jiebing Tan, Fei Xu, Wei Wang, Changqing Sun, Hongwen Deng, Yongli Yang, Xuezhong Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
metaCCA
autoimmune/autoinflammatory diseases
pleiotropic gene
GWAS
shared gene
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00030/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00030/full

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