Direct and Intervertebral DiscMediated Sensitization of Dorsal Root Ganglion Neurons by Hypoxia and Low pH

Objective Ischemia-related risk factors are consistently correlated with discogenic pain, but it remains unclear how the ischemia-associated hypoxia and acidosis influence the peripheral sensory nervous system, namely the dorsal root ganglion (DRG), either directly or indirectly via intervertebral d...

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Bibliographic Details
Main Authors: Junxuan Ma, Despina Stefanoska, Sibylle Grad, Mauro Alini, Marianna Peroglio
Format: Article
Language:English
Published: Korean Spinal Neurosurgery Society 2020-03-01
Series:Neurospine
Subjects:
Online Access:http://www.e-neurospine.org/upload/pdf/ns-2040052-026.pdf