Multitargeted Low-Dose GLAD Combination Chemoprevention: A Novel and Promising Approach to Combat Colon Carcinogenesis

Preclinical studies have shown that gefitinib, licofelone, atorvastatin, and α-difluoromethylornithine (GLAD) are promising colon cancer chemopreventive agents. Because low-dose combination regimens can offer potential additive or synergistic effects without toxicity, GLAD combination was tested fo...

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Bibliographic Details
Main Authors: Altaf Mohammed, Naveena B Janakiram, Misty Brewer, Krishna Vedala, Vernon E Steele, Chinthalapally V Rao
Format: Article
Language:English
Published: Elsevier 2013-05-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558613800346