Matrix Metalloproteinase-9-Dependent Release of IL-1β by Human Eosinophils

Asthma is often associated with airway eosinophilia, and therapies targeting eosinophils are now available to treat severe eosinophilic asthma. Eosinophilic asthma is often due to a type-2 immune response and production of IL-5, which leads to eosinophilopiesis and recruitment of mature eosinophils...

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Bibliographic Details
Main Authors: Stephane Esnault, Elizabeth A. Kelly, Sean H. Johnson, Larissa P. DeLain, Madeline J. Haedt, Andrea L. Noll, Nathan Sandbo, Nizar N. Jarjour
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2019/7479107