Tauroursodeoxycholic Acid Protects Retinal Pigment Epithelial Cells from Oxidative Injury and Endoplasmic Reticulum Stress In Vitro

Retinal degeneration is characterized by the dysfunction of retinal cells. Oxidative and endoplasmic reticulum (ER) stress play an important role in the pathogenesis and progression of retinal degeneration. Tauroursodeoxycholic acid (TUDCA) has been demonstrated to have protective effects in in vitr...

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Bibliographic Details
Main Authors: Reem Hasaballah Alhasani, Mohammad Almarhoun, Xinzhi Zhou, James Reilly, Steven Patterson, Zhihong Zeng, Xinhua Shu
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/8/9/367