T cell and periosteum cooperation in osteoclastogenesis induced by lipopolysaccharide injection in transplanted mouse tibia

Background/purpose: We previously reported that injedctions of lipopolysaccharide (LPS) into the gingiva of mice induce inflammatory bone resorption that actively involved T cells. Receptor activator of NF-κB ligand (RANKL), which is an essential factor for osteoclastogenesis, was reportedly produce...

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Bibliographic Details
Main Authors: Hiroki Kobayashi, Takashi Ukai, Chiaki Shiraishi, Yukio Ozaki, Atsutoshi Yoshimura, Yoshitaka Hara
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Journal of Dental Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1991790218300412