Humanized Mouse Model as a Novel Approach in the Assessment of Human Allogeneic Responses in Organ Transplantation

The outcome of organ transplantation is largely dictated by selection of a well-matched donor, which results in less chance of graft rejection. An allogeneic immune response is the main immunological barrier for successful organ transplantation. Donor and recipient human leukocyte antigen (HLA) mism...

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Bibliographic Details
Main Authors: Ashwin Ajith, Laura L. Mulloy, Md. Abu Musa, Valia Bravo-Egana, Daniel David Horuzsko, Imran Gani, Anatolij Horuzsko
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
HLA
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.687715/full