Angiopoietin-2 outperforms other endothelial biomarkers associated with severe acute kidney injury in patients with severe sepsis and respiratory failure

Angiopoietin-2 outperforms other endothelial biomarkers associated with severe acute kidney injury in patients with severe sepsis and respiratory failure

Abstract Background Endothelial dysfunction and injury is a major pathophysiologic feature of sepsis. Sepsis is also the most frequent cause of acute kidney injury (AKI) in critically ill patients. Though most studies of AKI in sepsis have focused on tubular epithelial injury, the role of endothelia...

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Bibliographic Details
Main Authors: Wen-Kuang Yu, J. Brennan McNeil, Nancy E. Wickersham, Ciara M. Shaver, Julie A. Bastarache, Lorraine B. Ware
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Critical Care
Subjects:
Endothelial dysfunction and injury
Sepsis
Angiopoietin-2
Acute kidney injury
Online Access:https://doi.org/10.1186/s13054-021-03474-z

Internet

https://doi.org/10.1186/s13054-021-03474-z

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